Description

2-(Methylsulfonyl)-2,5-Diazabicyclo[2.2.1]Heptane is a high-value, advanced pharmaceutical intermediate featuring a constrained bicyclic diazepane scaffold. This compound is of significant interest for its role as a key building block in modern medicinal chemistry, particularly for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs, enzyme inhibitors, and other bioactive molecules targeting complex disease pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Used in the development of selective ligands for various biological receptors and enzymes due to its rigid, three-dimensional structure.
• Protease Inhibitor Development: Employed in the design and synthesis of inhibitors for proteolytic enzymes, relevant in oncology and virology research.
• Chemical Biology Probes: Acts as a core structure for creating molecular probes to study biological pathways and protein functions.
• Asymmetric Synthesis: Its chiral, bicyclic framework makes it valuable for applications in asymmetric catalysis and the synthesis of enantiomerically pure compounds.

Basic Information

Product Name	2-(Methylsulfonyl)-2,5-Diazabicyclo[2.2.1]Heptane
CAS No.	944068-43-3
Molecular Formula	C7H14N2O2S
Molecular Weight	190.26 g/mol
Synonyms	2,5-Diazabicyclo[2.2.1]heptane, 2-(methylsulfonyl)-; 2-(Methanesulfonyl)-2,5-diazabicyclo[2.2.1]heptane; 2-Methylsulfonyl-2,5-diazabicyclo[2.2.1]heptane; 2,5-Diazabicyclo[2.2.1]heptane-2-methanesulfonate; 2,5-Diazabicyclo[2.2.1]heptane-2-sulfonylmethane; 944068-43-3; 2,5-Diazabicyclo[2.2.1]heptane, 2-(methylsulfonyl)- (9CI)
EINECS	Contact for details

Quality Control

Our 2-(Methylsulfonyl)-2,5-Diazabicyclo[2.2.1]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your research and development documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.