Description

trans-2-(4-n-Boc-Piperazin-1-Yl)Cyclohexanol is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Protease Inhibitor Development: Serves as a precursor in the creation of compounds designed to inhibit specific enzymatic pathways.
• Chemical Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing active pharmaceutical ingredients (APIs) under cGMP.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	trans-2-(4-n-Boc-Piperazin-1-Yl)Cyclohexanol
CAS No.	943906-69-2
Molecular Formula	C15H28N2O3
Molecular Weight	284.40 g/mol
Synonyms	trans-2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)cyclohexanol; 2-((4-(tert-Butoxycarbonyl)piperazin-1-yl)cyclohexanol (trans); 1-Boc-4-(trans-2-hydroxycyclohexyl)piperazine; trans-N-Boc-4-(2-hydroxycyclohexyl)piperazine; tert-Butyl 4-(trans-2-hydroxycyclohexyl)piperazine-1-carboxylate; BOC-Pip-CH-OH (trans); 943906-69-2; trans-2-(4-N-Boc-piperazinyl)cyclohexanol
EINECS	Contact for details

Quality Control

Our trans-2-(4-n-Boc-Piperazin-1-Yl)Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (trans-isomer), and impurity profiles is provided with every shipment. We support development with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a controlled humidity environment to prevent degradation. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Isomeric Purity (trans-isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.