Description

4-(2,6-Dimethylmorpholin-4-Yl)-3-Nitrobenzoic Acid CAS NO 942474-64-8 is a high-purity, advanced pharmaceutical intermediate characterized by its morpholine and nitro-substituted benzoic acid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Synthesis: Serves as a precursor for the manufacture of more complex, high-value specialty chemicals.
• Academic & Contract Research: Employed in university and CRO laboratories for the development of new synthetic methodologies and heterocyclic chemistry.
• Chemical Library Development: A valuable component for creating diverse screening libraries for high-throughput biological testing.

Basic Information

Product Name	4-(2,6-Dimethylmorpholin-4-Yl)-3-Nitrobenzoic Acid
CAS No.	942474-64-8
Molecular Formula	C13H16N2O5
Molecular Weight	280.28 g/mol
Synonyms	3-Nitro-4-(2,6-dimethylmorpholin-4-yl)benzoic acid; Benzoic acid, 3-nitro-4-(2,6-dimethyl-4-morpholinyl)-; 4-(2,6-Dimethyl-4-morpholinyl)-3-nitrobenzoic acid; 942474-64-8; 4-(2,6-Dimethylmorpholin-4-yl)-3-nitrobenzoic acid
EINECS	Contact for details

Quality Control

Our 4-(2,6-Dimethylmorpholin-4-Yl)-3-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions. For long-term storage, consider using an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.