Description

1-(2-Cyanophenyl)Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Serves as a core scaffold for constructing novel active pharmaceutical ingredients in pre-clinical and clinical development.
• Chemical Biology: Employed as a probe or ligand in biochemical assays to study protein interactions and enzyme function.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	1-(2-Cyanophenyl)Piperidine-3-Carboxylic Acid
CAS No.	942474-51-3
Molecular Formula	C13H14N2O2
Molecular Weight	230.26 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-(2-cyanophenyl)-; 1-(2-Cyanophenyl)-3-piperidinecarboxylic acid; 1-(2-Cyanophenyl)piperidine-3-carboxylic acid; 942474-51-3; 1-(2-Cyanophenyl)nipecotic acid; 2-(3-Carboxypiperidin-1-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 1-(2-Cyanophenyl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.