Description

1-[2-Chloro-4-(Methylsulfonyl)Phenyl]-4-Hydroxypiperidine is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure featuring a chlorophenyl and methylsulfonyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex piperidine-based heterocyclic compounds.
• Agrochemical Development: Serves as a precursor in the exploration of new pesticides and herbicides due to its bioactive scaffold.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Material Science Research: Investigated for potential use in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-[2-Chloro-4-(Methylsulfonyl)Phenyl]-4-Hydroxypiperidine
CAS No.	942474-26-2
Molecular Formula	C12H16ClNO3S
Molecular Weight	289.78 g/mol
Synonyms	4-Hydroxy-1-[2-chloro-4-(methylsulfonyl)phenyl]piperidine; 1-(2-Chloro-4-methanesulfonylphenyl)-4-hydroxypiperidine; 942474-26-2; 4-Hydroxy-1-(2-chloro-4-methylsulfonylphenyl)piperidine; 1-(2-Chloro-4-(methylsulfonyl)phenyl)piperidin-4-ol; 4-Piperidinol, 1-[2-chloro-4-(methylsulfonyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-[2-Chloro-4-(Methylsulfonyl)Phenyl]-4-Hydroxypiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.