Description

9-Boc-3,9-Diaza-Bicyclo[3.3.1]Nonane CAS NO 941295-31-4 is a high-purity, protected bicyclic diamine building block of significant importance in advanced organic synthesis. Its core value lies in providing a rigid, nitrogen-containing scaffold that is crucial for constructing complex molecular architectures, particularly in pharmaceutical research. This compound is primarily needed by medicinal chemists and process development scientists working on new drug candidates, especially within the fields of central nervous system (CNS) therapeutics and protease inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and antiviral drug discovery pipelines.
• Medicinal Chemistry Scaffold: Serves as a privileged structure for constructing libraries of compounds targeting G-protein coupled receptors (GPCRs) and various enzymes.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The bicyclic structure mimics peptide turn motifs, making it valuable for creating stable peptidomimetics with enhanced bioavailability.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study biological pathways and protein function.
• Asymmetric Synthesis: Acts as a chiral auxiliary or precursor for chiral catalysts in stereoselective transformations.

Basic Information

Product Name	9-Boc-3,9-Diaza-Bicyclo[3.3.1]Nonane
CAS No.	941295-31-4
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	3,9-Diaza-bicyclo[3.3.1]nonane, 9-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 3,9-diazabicyclo[3.3.1]nonane-9-carboxylate; 9-Boc-3,9-diazabicyclo[3.3.1]nonane; 9-(tert-Butoxycarbonyl)-3,9-diazabicyclo[3.3.1]nonane; BOC-DABN; 3,9-Diazabicyclo[3.3.1]nonane-9-carboxylic acid tert-butyl ester; 9-N-Boc-3,9-diazabicyclo[3.3.1]nonane
EINECS	Contact for details

Quality Control

Every batch of 9-Boc-3,9-Diaza-Bicyclo[3.3.1]Nonane is manufactured and tested under strict quality management systems. We ensure compliance with cGMP guidelines where applicable for pharmaceutical intermediates. Our rigorous quality testing includes identity confirmation, purity assay, and impurity profiling using advanced analytical techniques. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for each lot to guarantee traceability and consistency for your critical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.