Description

(4-Methanesulfonyl-Piperazin-1-Yl)-Acetic Acid is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates, particularly due to its sulfonyl and acetic acid functional groups which enable diverse chemical modifications. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry: Used as a versatile scaffold for constructing compound libraries via parallel synthesis and structure-activity relationship (SAR) studies.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and target engagement.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for drug candidates.
• Ligand and Catalyst Development: Potential use in designing novel ligands for metal catalysis or as a component of organocatalysts.

Basic Information

Product Name	(4-Methanesulfonyl-Piperazin-1-Yl)-Acetic Acid
CAS No.	939756-87-3
Molecular Formula	C7H14N2O4S
Molecular Weight	222.26 g/mol
Synonyms	2-(4-Methanesulfonylpiperazin-1-yl)acetic Acid; 1-(Carboxymethyl)-4-(methylsulfonyl)piperazine; 4-(Methylsulfonyl)-1-piperazineacetic Acid; (4-Methylsulfonyl-1-piperazinyl)acetic Acid; 1-Piperazineacetic Acid, 4-(methylsulfonyl)-; Acetic Acid, (4-methanesulfonyl-1-piperazinyl)-; (4-Methanesulfonylpiperazin-1-yl)acetic Acid
EINECS	Contact for details

Quality Control

Our (4-Methanesulfonyl-Piperazin-1-Yl)-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects requiring material that meets GMP or other stringent regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.