Description

n-((3-Chloropyrazin-2-Yl)Methyl)-3-Oxocyclobutanecarboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining a chloropyrazine moiety with a cyclobutanecarboxamide core. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting specific biological pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise building block to develop next-generation therapeutic agents, including potential kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, particularly for target identification and lead optimization.
• Kinase Inhibitor Synthesis: Used in the synthetic pathways for developing potential kinase inhibitors, a major class of therapeutics in oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the custom synthesis of complex molecules for clinical trials.
• Biochemical Tool Compound: May be utilized in life science research as a probe or tool compound to study specific enzyme or receptor functions.
• Agrochemical Intermediate: Potential application in the synthesis of advanced agrochemicals, leveraging the bioactive pyrazine heterocycle.

Basic Information

Product Name	n-((3-Chloropyrazin-2-Yl)Methyl)-3-Oxocyclobutanecarboxamide
CAS No.	939412-84-7
Molecular Formula	C10H10ClN3O2
Molecular Weight	239.66 g/mol
Synonyms	3-Oxocyclobutanecarboxamide, N-[(3-chloro-2-pyrazinyl)methyl]-; N-[(3-Chloropyrazin-2-yl)methyl]-3-oxocyclobutanecarboxamide; 3-Oxocyclobutanecarboxylic acid [(3-chloro-2-pyrazinyl)methyl]amide; 939412-84-7; AKOS025147324; N-((3-Chloropyrazin-2-yl)methyl)-3-oxocyclobutanecarboxamide; CS-0476645; FT-0778087
EINECS	Contact for details

Quality Control

Our n-((3-Chloropyrazin-2-Yl)Methyl)-3-Oxocyclobutanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.