Description

1-(4-Methylbenzyl)Piperazin-2-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Scaffold: Used as a core structure or building block for creating compound libraries in drug discovery programs for high-throughput screening.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its piperazinone moiety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic & Institutional Research: A valuable reagent for universities and research institutes conducting studies in synthetic methodology and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	1-(4-Methylbenzyl)Piperazin-2-One
CAS No.	938458-91-4
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	1-[(4-Methylphenyl)methyl]-2-piperazinone; 1-(4-Methylbenzyl)-2-piperazinone; 1-(p-Tolylmethyl)piperazin-2-one; 2-Piperazinone, 1-[(4-methylphenyl)methyl]-; 938458-91-4; 1-(4-Methylbenzyl)piperazin-2-one; 1-(4-Methylbenzyl)-2-piperazinone
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Methylbenzyl)Piperazin-2-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.