Description

17(R)-Resolvin D1 Methyl Ester is a specialized methylated derivative of the potent pro-resolving lipid mediator Resolvin D1. This compound is of significant interest for its enhanced stability and utility in biochemical and pharmacological research focused on inflammation resolution pathways. It serves as a critical reference standard and research tool for scientists in pharmaceutical development, immunology, and metabolic disease studies, enabling precise investigation into the mechanisms of chronic inflammatory conditions.

Application

• Biochemical Research: Used as a high-purity reference standard in analytical studies (HPLC, LC-MS) to quantify endogenous resolvin levels.
• Pharmacology & Drug Discovery: Serves as a key intermediate or molecular tool for screening and developing novel anti-inflammatory therapeutics targeting specialized pro-resolving mediator (SPM) pathways.
• Cell Biology & Immunology: Applied in in vitro cell culture models to study the specific roles and signaling mechanisms of 17(R)-Resolvin D1 in inflammation resolution, immune modulation, and tissue repair.
• Metabolic Disease Research: Investigated for its potential effects in models of metabolic syndrome, including insulin resistance and non-alcoholic fatty liver disease (NAFLD).
• Academic Research: Essential for universities and research institutes conducting fundamental studies on the biosynthesis and biological activities of lipid mediators.

Basic Information

Product Name	17(R)-Resolvin D1 Methyl Ester
CAS No.	937738-64-2
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	17(R)-RvD1 Methyl Ester; (4Z,7R,8E,10Z,12E,14S,16Z,17R,19Z)-7,8,17-Trihydroxy-4,10,12,14,16,19-docosahexaenoic Acid Methyl Ester; 17R-Resolvin D1 Me ester; Methyl (4Z,7R,8E,10Z,12E,14S,16Z,17R,19Z)-7,8,17-trihydroxydocosa-4,10,12,14,16,19-hexaenoate; 17R-RvD1-Me; Aspirin-Triggered Resolvin D1 Methyl Ester (AT-RvD1-Me); 17R-Dihydroxy-docosahexaenoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of 17(R)-Resolvin D1 Methyl Ester is manufactured and analyzed under strict quality protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identification, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.