Description

Resolvin D1 Methyl Ester is a specialized methylated derivative of the potent pro-resolving lipid mediator Resolvin D1. This compound is of significant interest for research into the resolution phase of inflammation and related biological pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in the development of novel therapeutic agents for inflammatory and autoimmune diseases.

Application

• Biomedical Research: A critical reference standard and tool for studying the mechanisms of inflammation resolution, cellular signaling, and immune modulation.
• Drug Discovery & Development: Used as a lead compound or biochemical probe in screening assays and preclinical studies targeting chronic inflammatory conditions.
• Metabolic Pathway Analysis: Employed in metabolomics and lipidomics research to map and understand specialized pro-resolving mediator (SPM) biosynthesis and function.
• In Vitro & In Vivo Studies: Applied in cell culture and animal models to investigate the therapeutic potential of resolvin analogs in diseases like arthritis, dermatitis, and periodontal disease.
• Analytical Standard: Serves as a high-purity standard for the qualitative and quantitative analysis (e.g., via LC-MS/MS) of resolvins in complex biological samples.

Basic Information

Product Name	Resolvin D1 Methyl Ester
CAS No.	937738-63-1
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	7S,8R,17S-Trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic Acid Methyl Ester; RvD1 Methyl Ester; Resolvin D1 Me Ester; Methyl (4Z,7S,8R,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,11,13,15,19-pentaenoate
EINECS	Contact for details

Quality Control

Our Resolvin D1 Methyl Ester is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods including HPLC and mass spectrometry. We adhere to cGMP principles for research-grade materials to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed vial at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.