Description

3-Bromopyrazine-2-Carboxylic Acid is a versatile and high-purity brominated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key precursor in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for designing and synthesizing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity bromopyrazine derivatives.

Basic Information

Product Name	3-Bromopyrazine-2-Carboxylic Acid
CAS No.	937669-80-2
Molecular Formula	C5H3BrN2O2
Molecular Weight	202.99 g/mol
Synonyms	2-Bromo-3-pyrazinecarboxylic Acid; 3-Bromo-2-pyrazinecarboxylic Acid; 3-Bromopyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 3-bromo-; 3-Bromopyrazinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Bromopyrazine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production use. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for GMP (Good Manufacturing Practice) applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.