Description

Ethyl 4-[2-(4-Hydroxypiperidin-1-yl)ethoxy]benzoate is a high-purity synthetic organic compound featuring a benzoate ester core linked to a hydroxypiperidine moiety via an ethoxy spacer. This specific molecular architecture makes it a critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted receptor modulation. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) in new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes for the production of complex, high-value APIs.
• Biochemical Tool Compound: Potential use in biochemical assays and as a reference standard for pharmacological studies.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals requiring a specific piperidine-benzoate hybrid structure.

Basic Information

Product Name	Ethyl 4-[2-(4-Hydroxypiperidin-1-yl)ethoxy]benzoate
CAS No.	937601-92-8
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	Ethyl 4-(2-(4-hydroxypiperidin-1-yl)ethoxy)benzoate; 1-[2-(4-Ethoxycarbonylphenoxy)ethyl]-4-hydroxypiperidine; Benzoic acid, 4-[2-(4-hydroxy-1-piperidinyl)ethoxy]-, ethyl ester; 4-[2-(4-Hydroxypiperidin-1-yl)ethoxy]benzoic acid ethyl ester; Ethyl p-[2-(4-hydroxypiperidino)ethoxy]benzoate; 937601-92-8
EINECS	Contact for details

Quality Control

Our Ethyl 4-[2-(4-Hydroxypiperidin-1-yl)ethoxy]benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for use in advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.