Description

Methyl 4-[2-(4-Benzylpiperazin-1-Yl)Ethoxy]Benzoate is a high-purity pharmaceutical intermediate featuring a benzylpiperazine and benzoate ester structure. This compound is valued for its role as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily sought by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, especially those targeting neurological pathways.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Research: Serves as a versatile scaffold for synthesizing libraries of compounds for biological screening.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Process Chemistry: Integrated into scalable synthetic routes for the production of target molecules under GMP-like conditions.

Basic Information

Product Name	Methyl 4-[2-(4-Benzylpiperazin-1-Yl)Ethoxy]Benzoate
CAS No.	937601-91-7
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Methyl 4-[2-(4-benzyl-1-piperazinyl)ethoxy]benzoate; Benzoic acid, 4-[2-(4-benzyl-1-piperazinyl)ethoxy]-, methyl ester; 937601-91-7; 4-[2-(4-Benzylpiperazin-1-yl)ethoxy]benzoic acid methyl ester; Methyl p-[2-(4-benzylpiperazin-1-yl)ethoxy]benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-[2-(4-Benzylpiperazin-1-Yl)Ethoxy]Benzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement in-process controls and final release testing, including advanced chromatographic methods, to meet the exacting standards required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.