Description

3-(2-Hydroxyethyl)Piperazin-2-One is a versatile heterocyclic building block and pharmaceutical intermediate. This compound is valued for its unique piperazinone core functionalized with a hydroxylethyl side chain, enabling its use in complex synthetic pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular diseases.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing piperazine and piperazinone-based scaffolds in drug discovery programs.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands used in catalysis and metal complexation.
• Bioconjugation Reagent: The hydroxyl group provides a handle for linking to other molecules, useful in bioconjugation and probe development.
• Polymer Modification: Can be incorporated into polymer chains to impart specific chemical functionality or biocompatibility.
• Agrochemical Research: Employed in the research and development of novel agrochemicals and plant growth regulators.

Basic Information

Product Name	3-(2-Hydroxyethyl)Piperazin-2-One
CAS No.	936940-62-4
Molecular Formula	C6H12N2O2
Molecular Weight	144.17 g/mol
Synonyms	2-(2-Oxo-1-piperazinyl)ethanol; 1-(2-Hydroxyethyl)-2-piperazinone; 2-(2-Oxopiperazin-1-yl)ethanol; 2-Hydroxyethylpiperazin-2-one; N-(2-Hydroxyethyl)-2-piperazinone; 1-Piperazineethanol, 2-oxo-; 936940-62-4
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxyethyl)Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.