Description

(1S,3S)-3-(8-Bromo-1-Chloroh-Pyrrolo[1,2-A]Pyrazin-6-Yl)-1-Methylcyclobutanol is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and halogenated heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for complex small molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Development & Scale-Up: Serves as a critical raw material for developing and scaling robust, GMP-compliant synthetic routes for new APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies in preclinical and early-phase clinical development.
• Academic Research: Employed in university and institutional labs for exploring new synthetic methodologies involving pyrrolopyrazine scaffolds.

Basic Information

Item	Detail
Product Name	(1S,3S)-3-(8-Bromo-1-Chloroh-Pyrrolo[1,2-A]Pyrazin-6-Yl)-1-Methylcyclobutanol
CAS No.	936901-74-5
Molecular Formula	C13H12BrClN2O
Molecular Weight	327.60 g/mol
Synonyms	(1S,3S)-3-(8-Bromo-1-chloro-1H-pyrrolo[1,2-a]pyrazin-6-yl)-1-methylcyclobutanol; (1S,3S)-3-(8-Bromo-1-chloro-1H-pyrrolo[1,2-a]pyrazin-6-yl)-1-methyl-1-cyclobutanol; 936901-74-5; (1S,3S)-3-(8-Bromo-1-chloro-pyrrolo[1,2-a]pyrazin-6-yl)-1-methylcyclobutanol; 1-Methyl-3-(8-bromo-1-chloro-1H-pyrrolo[1,2-a]pyrazin-6-yl)cyclobutanol (1S,3S)-; Pyrrolo[1,2-a]pyrazine intermediate
EINECS	Contact for details

Quality Control

Our production of (1S,3S)-3-(8-Bromo-1-Chloroh-Pyrrolo[1,2-A]Pyrazin-6-Yl)-1-Methylcyclobutanol adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.