Description

3-(1-Chloroh-Pyrrolo[1,2-A]Pyrazin-6-Yl)Cyclobutanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial value as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially for central nervous system (CNS) and oncology targets.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex pyrrolopyrazine-based scaffolds, enabling structure-activity relationship (SAR) studies.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing novel synthetic methodologies.
• Agrochemical Research: Potential application as an intermediate in the discovery of new crop protection agents with novel modes of action.

Basic Information

Product Name	3-(1-Chloroh-Pyrrolo[1,2-A]Pyrazin-6-Yl)Cyclobutanone
CAS No.	936901-72-3
Molecular Formula	C12H9ClN2O
Molecular Weight	232.66 g/mol
Synonyms	3-(1-Chloro-1H-pyrrolo[1,2-a]pyrazin-6-yl)cyclobutanone; 3-(1-Chloro-1H-pyrrolo[1,2-a]pyrazin-6-yl)cyclobutan-1-one; 1-Chloro-6-(3-oxocyclobutyl)pyrrolo[1,2-a]pyrazine; Cyclobutanone, 3-(1-chloro-1H-pyrrolo[1,2-a]pyrazin-6-yl)-; 936901-72-3; 3-(1-Chloro-pyrrolo[1,2-a]pyrazin-6-yl)-cyclobutanone
EINECS	Contact for details

Quality Control

Our production of 3-(1-Chloroh-Pyrrolo[1,2-A]Pyrazin-6-Yl)Cyclobutanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.