Description

2-Pyrazinecarboxamide, 3-[(5-Chloro-2-Fluorobenzoyl)Amino]- is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrazinecarboxamide structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up processes for new APIs requiring a functionalized pyrazine core.
• Biochemical Research: Serves as a reagent or precursor in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	2-Pyrazinecarboxamide, 3-[(5-Chloro-2-Fluorobenzoyl)Amino]-
CAS No.	936564-98-6
Molecular Formula	C12H8ClFN4O2
Molecular Weight	294.67 g/mol
Synonyms	3-[(5-Chloro-2-fluorobenzoyl)amino]pyrazine-2-carboxamide; 3-Amino-N-(5-chloro-2-fluorobenzoyl)pyrazine-2-carboxamide; 936564-98-6; 5-Chloro-2-fluoro-N-[2-(aminocarbonyl)pyrazin-3-yl]benzamide; UNII-9K5J0Q305O; Benzamide, 5-chloro-2-fluoro-N-[2-(aminocarbonyl)-3-pyrazinyl]-; 9K5J0Q305O
EINECS	Contact for details

Quality Control

Our 2-Pyrazinecarboxamide, 3-[(5-Chloro-2-Fluorobenzoyl)Amino]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.