Description

tert-Butyl 4-(4-Methoxybenzyl)Piperazine-1-Carboxylate CAS NO 936330-00-6 is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new drug candidates, especially within the fields of central nervous system (CNS) agents and receptor modulators.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Peptidomimetic Synthesis: Serves as a constrained scaffold to mimic peptide secondary structures in drug design.
• Ligand Development: Employed in the creation of selective ligands for G-protein-coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A foundational unit for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(4-Methoxybenzyl)Piperazine-1-Carboxylate
CAS No.	936330-00-6
Molecular Formula	C17H26N2O3
Molecular Weight	306.40 g/mol
Synonyms	1-Boc-4-(4-Methoxybenzyl)piperazine; tert-Butyl 4-[(4-Methoxyphenyl)methyl]piperazine-1-carboxylate; 4-(4-Methoxybenzyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-methoxybenzyl)piperazine; N-Boc-4-(4-Methoxybenzyl)piperazine; BOC-4-(4-Methoxybenzyl)piperazine; 936330-00-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Methoxybenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material traceability and reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.