Description

Tebipenem Tetrahydrate CAS NO 936010-57-0 is a novel, orally bioavailable carbapenem antibiotic prodrug. This compound is of significant commercial and clinical interest as it represents a breakthrough in oral carbapenem therapy, addressing the critical need for effective outpatient treatment of serious bacterial infections. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development of advanced antibacterial agents, particularly for drug-resistant Gram-negative pathogens.

Application

• Pharmaceutical Active Ingredient (API): Serves as the key active component in the formulation of oral antibiotic medications.
• Clinical Research & Development: Used in preclinical and clinical studies for evaluating efficacy against multi-drug resistant bacteria.
• Antibacterial Agent Synthesis: Acts as a crucial intermediate or final compound in the synthesis of novel carbapenem derivatives.
• Microbiology & In-vitro Studies: Employed in laboratory settings for antimicrobial susceptibility testing and mechanism of action research.
• Reference Standard: Used as a high-purity standard in analytical laboratories for quality control and method validation of pharmaceutical products.

Basic Information

Product Name	Tebipenem Tetrahydrate
CAS No.	936010-57-0
Molecular Formula	C₂₂H₃₁N₅O₈S₂ • 4H₂O
Molecular Weight	637.68 g/mol (Tetrahydrate)
Synonyms	Tebipenem Pivoxil Tetrahydrate; Tebipenem Pivoxil Hydrochloride Tetrahydrate; (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Pivaloyloxymethyl Ester Tetrahydrate; L-084; ME1211; Orapenem; SPRI-98; SPRI 98
EINECS	Contact for details

Quality Control

Our Tebipenem Tetrahydrate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, purity, and identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	10.0% - 13.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.