Description

Tebipenem Pivoxil is an orally bioavailable prodrug of the carbapenem antibiotic tebipenem. This compound is of significant commercial interest as it represents a key advancement in oral antibiotic therapy, offering a convenient alternative to intravenous administration for serious bacterial infections. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation antibacterial agents targeting multi-drug resistant pathogens.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of oral antibiotic medications.
• Clinical Research: Used in preclinical and clinical studies for evaluating efficacy against Gram-positive and Gram-negative bacteria.
• Antibacterial Drug Development: Serves as a critical intermediate or reference standard in R&D for novel carbapenem derivatives.
• Veterinary Medicine: Potential application in developing antibacterial treatments for veterinary use.
• Microbiological Studies: Used as a reference compound in antimicrobial susceptibility testing and resistance mechanism studies.

Basic Information

Product Name	Tebipenem Pivoxil
CAS No.	161715-24-8
Molecular Formula	C₂₂H₃₁N₅O₉S₂
Molecular Weight	573.64 g/mol
Synonyms	Tebipenem Pivoxil; Tebipenem Pivoxil Hydrate; (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Pivaloyloxymethyl Ester; L-084; ME1211; Orapenem; SP-059
EINECS	Contact for details

Quality Control

Our Tebipenem Pivoxil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.