Description

Biapenem is a carbapenem antibiotic belonging to the β-lactam class, known for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria. This compound is a critical active pharmaceutical ingredient (API) valued for its stability against hydrolysis by many β-lactamases. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of injectable antibiotic formulations and as a reference standard in analytical studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of sterile injectable antibiotic drugs.
• Antimicrobial Research: Serves as a key reference compound in microbiological and pharmacological studies for evaluating new antibacterial agents.
• Hospital Formulations: Used in the preparation of specialized antibiotic solutions for treating severe, multi-drug resistant infections in clinical settings.
• Veterinary Medicine: Potential application in developing treatments for bacterial infections in animals.
• Analytical Standard: High-purity grade used for quality control, method validation, and calibration in HPLC and other chromatographic systems.

Basic Information

Item	Detail
Product Name	Biapenem
CAS No.	120410-24-4
Molecular Formula	C15H18N4O4S
Molecular Weight	350.39 g/mol
Synonyms	Biapenem; LJC 10,627; L-627; (4R,5S,6S)-3-[[(3S,5S)-5-[(S)-3-Hydroxybutyrylamido]pyrrolidin-3-yl]thio]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; L-627 Antibiotic; LJC10627; Antibiotic LJC 10,627
EINECS	Contact for details

Quality Control

Our Biapenem is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, impurities, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	< 0.05 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.