Description

tert-Butyl 3-Oxotetrahydro-1H-Oxazolo[3,4-A]Pyrazine-7(3H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused bicyclic structure. This compound is of significant value for enabling sophisticated synthetic routes in modern drug discovery and development. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, especially those containing fused heterocyclic systems.
• Protease Inhibitor Research: Serves as a crucial precursor in the development of inhibitors targeting specific proteases, which are relevant in virology and oncology.
• Peptidomimetic Chemistry: Used to construct constrained peptide analogs and peptidomimetics, enhancing metabolic stability and bioavailability of potential therapeutics.
• Medicinal Chemistry & SAR Studies: Enables structure-activity relationship (SAR) exploration by providing a versatile scaffold for introducing diverse functional groups.
• Contract Research & Development (CRO/CDMO): Supplied to organizations specializing in custom synthesis and process development for client-sponsored drug programs.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 3-Oxotetrahydro-1H-Oxazolo[3,4-A]Pyrazine-7(3H)-Carboxylate
CAS No.	935544-47-1
Molecular Formula	C11H16N2O4
Molecular Weight	240.26 g/mol
Synonyms	7-(tert-Butoxycarbonyl)-3-oxohexahydro-1H-oxazolo[3,4-a]pyrazine; tert-Butyl 3-oxo-1,3,4,6,7,8-hexahydro-2H-oxazolo[3,4-a]pyrazine-7-carboxylate; 1H-Oxazolo[3,4-a]pyrazine-7(3H)-carboxylic acid, 2,3,4,6,7,8-hexahydro-3-oxo-, 1,1-dimethylethyl ester; BOC-protected oxazolopyrazinone; (3aS,7aR)-tert-Butyl 3-oxooctahydro-1H-oxazolo[3,4-a]pyrazine-7-carboxylate (stereoisomer); Oxazolopyrazine derivative CAS 935544-47-1
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Oxotetrahydro-1H-Oxazolo[3,4-A]Pyrazine-7(3H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.