Description

tert-Butyl (3S)-3-(Piperidin-4-Yloxy)Pyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a chiral pyrrolidine-piperidine ether scaffold. This compound matters for its critical role as a key building block in the synthesis of complex, biologically active molecules, particularly in drug discovery and development. Pharmaceutical researchers and fine chemical manufacturers need it for creating novel therapeutic candidates, especially in areas targeting the central nervous system and other specialized receptor classes.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Neurological & CNS-Targeted Research: Its structural motif is valuable for developing ligands and modulators for neurological targets.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic & Institutional Research: Utilized in chemical biology and pharmacology research programs investigating new therapeutic pathways.

Basic Information

Product Name	tert-Butyl (3S)-3-(Piperidin-4-Yloxy)Pyrrolidine-1-Carboxylate
CAS No.	935534-13-7
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	1-Boc-3-((4-piperidyl)oxy)-(3S)-pyrrolidine; (3S)-1-(tert-Butoxycarbonyl)-3-(4-piperidinyloxy)pyrrolidine; tert-Butyl 3-((piperidin-4-yl)oxy)-(3S)-pyrrolidine-1-carboxylate; 1-Boc-3S-(4-piperidyloxy)pyrrolidine; (S)-tert-Butyl 3-(piperidin-4-yloxy)pyrrolidine-1-carboxylate; 935534-13-7; (3S)-3-(Piperidin-4-yloxy)pyrrolidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S)-3-(Piperidin-4-Yloxy)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent specifications for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.