Description

cis-3,5-Dimethyl-1-(4-(Trifluoromethoxy)Phenyl)Piperazine Hydrochloride is a high-purity, synthetically derived piperazine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a structurally defined, functionalized scaffold essential for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is primarily needed by pharmaceutical R&D laboratories, process chemistry teams, and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Utilized in pharmacological studies as a ligand or probe to investigate specific biological pathways and protein interactions.

Basic Information

Product Name	cis-3,5-Dimethyl-1-(4-(Trifluoromethoxy)Phenyl)Piperazine Hydrochloride
CAS No.	934760-93-7
Molecular Formula	C13H18F3N2O•HCl
Molecular Weight	308.75 g/mol
Synonyms	1-(4-(Trifluoromethoxy)phenyl)-cis-3,5-dimethylpiperazine hydrochloride; cis-3,5-Dimethyl-1-[4-(trifluoromethoxy)phenyl]piperazine hydrochloride; 3,5-Dimethyl-1-(4-trifluoromethoxyphenyl)piperazine hydrochloride (cis-); 934760-93-7; (cis)-3,5-Dimethyl-1-(4-(trifluoromethoxy)phenyl)piperazine HCl; 1-(4-Trifluoromethoxyphenyl)-3,5-dimethylpiperazine hydrochloride (cis-)
EINECS	Contact for details

Quality Control

Our cis-3,5-Dimethyl-1-(4-(Trifluoromethoxy)Phenyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.