Description

1-Benzyl-3-((tert-Butyldimethylsilyloxy)Methyl)Piperidin-4-Ol CAS NO 934536-18-2 is a sophisticated, multi-functional piperidine derivative featuring both a benzyl protecting group and a tert-butyldimethylsilyl (TBDMS) ether moiety. This compound is a critical advanced pharmaceutical intermediate (API) valued for its role in constructing complex nitrogen-containing heterocycles. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams engaged in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology spaces.

Application

• Key Intermediate in Drug Discovery: Serves as a pivotal building block for synthesizing novel piperidine-based drug candidates targeting various receptors.
• Pharmaceutical Active Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules for preclinical and clinical development.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a versatile scaffold for further functionalization.
• Synthesis of Neurologically Active Compounds: Particularly relevant for developing potential treatments for neurological disorders, pain management, and psychiatric conditions.
• Production of Specialty Fine Chemicals: Employed in the manufacture of high-value, low-volume chemicals for research and specialized industrial applications.
• Academic and Contract Research Organization (CRO) Projects: Supports synthetic chemistry research in academic institutions and outsourcing facilities.

Basic Information

Product Name	1-Benzyl-3-((tert-Butyldimethylsilyloxy)Methyl)Piperidin-4-Ol
CAS No.	934536-18-2
Molecular Formula	C19H33NO2Si
Molecular Weight	335.56 g/mol
Synonyms	4-Piperidinol, 1-benzyl-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-; 1-Benzyl-3-((tert-butyldimethylsilyloxy)methyl)piperidin-4-ol; 1-Benzyl-3-((TBDMS-oxy)methyl)piperidin-4-ol; 3-((tert-Butyldimethylsilyloxy)methyl)-1-benzylpiperidin-4-ol; 1-Benzyl-3-((tert-butyldimethylsilyloxy)methyl)-4-hydroxypiperidine; 1-Benzyl-3-(TBDMS-oxymethyl)-4-piperidinol; 4-Hydroxy-1-benzyl-3-((TBDMS-oxy)methyl)piperidine
EINECS	Contact for details

Quality Control

Our production of 1-Benzyl-3-((tert-Butyldimethylsilyloxy)Methyl)Piperidin-4-Ol adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We support cGMP-compliant manufacturing standards for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.