Description

3-(1H-1,2,4-Triazol-5-Yl)Piperidine is a high-value nitrogen-containing heterocyclic building block with significant utility in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its fused triazole-piperidine structure imparts desirable biological activity and pharmacokinetic properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in the development of new generation fungicides, herbicides, and plant growth regulators due to its bioactive heterocyclic core.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: A versatile building block for constructing complex nitrogen heterocycles in custom synthesis and contract manufacturing.

Basic Information

Product Name	3-(1H-1,2,4-Triazol-5-Yl)Piperidine
CAS No.	933750-46-0
Molecular Formula	C7H12N4
Molecular Weight	152.20 g/mol
Synonyms	5-(Piperidin-3-yl)-1H-1,2,4-triazole; 3-(1H-1,2,4-Triazol-5-yl)piperidine; 1H-1,2,4-Triazole, 5-(3-piperidinyl)-; Piperidine, 3-(1H-1,2,4-triazol-5-yl)-; 933750-46-0; 3-(1H-1,2,4-Triazol-5-yl)piperidine; 5-(3-Piperidyl)-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our 3-(1H-1,2,4-Triazol-5-Yl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.