Description

2-Piperazinecarboxylic Acid, 1-Methyl-3-Oxo- is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique piperazine scaffold functionalized with both a carboxylic acid and a keto group makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel piperazine-based drug candidates, including potential central nervous system (CNS) agents, antimicrobials, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the piperazine moiety can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Peptidomimetic Research: Employed in medicinal chemistry to design and synthesize peptide analogs and conformationally restricted scaffolds.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) and research institutions for custom synthesis projects and library production.
• Chemical Reference Standard: Provided as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Piperazinecarboxylic Acid, 1-Methyl-3-Oxo-
CAS No.	933684-30-1
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	1-Methyl-3-oxopiperazine-2-carboxylic acid; 1-Methyl-2-carboxy-3-oxopiperazine; 3-Oxo-1-methylpiperazine-2-carboxylic acid; 2-Carboxy-1-methyl-3-oxopiperazine; 1-Methyl-3-oxo-2-piperazinecarboxylic acid; Methyl-oxo-piperazinecarboxylic acid; (1-Methyl-3-oxopiperazin-2-yl)formic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Piperazinecarboxylic Acid, 1-Methyl-3-Oxo- is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.