Description

Ethyl n-Boc-4-(4-Methoxybenzyl)Piperidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine carboxylic acid ester structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing routes.
• Protease Inhibitor Synthesis: The protected piperidine scaffold is valuable for constructing inhibitors of various proteolytic enzymes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and methodology development.

Basic Information

Product Name	Ethyl n-Boc-4-(4-Methoxybenzyl)Piperidine-4-Carboxylate
CAS No.	932710-58-2
Molecular Formula	C21H31NO5
Molecular Weight	377.48 g/mol
Synonyms	Ethyl 4-[(4-methoxyphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylate; 1-Boc-4-(4-Methoxybenzyl)-4-piperidinecarboxylic Acid Ethyl Ester; 1-(tert-Butoxycarbonyl)-4-(4-methoxybenzyl)piperidine-4-carboxylic Acid Ethyl Ester; 4-(4-Methoxybenzyl)-1-Boc-piperidine-4-carboxylic Acid Ethyl Ester; Ethyl 1-Boc-4-(4-methoxybenzyl)-4-piperidinecarboxylate; tert-Butyl 4-(ethoxycarbonyl)-4-(4-methoxybenzyl)piperidine-1-carboxylate; 1-N-Boc-4-(4-Methoxybenzyl)isonipecotic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl n-Boc-4-(4-Methoxybenzyl)Piperidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.