Description

tert-Butyl 2-cyano-2-(pyrazin-2-yl)acetate is a high-value, versatile chemical building block featuring a reactive cyanoacetate ester group adjacent to a pyrazine heterocycle. This compound matters for its critical role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyrazine or dihydropyrazine motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing molecular libraries in drug discovery programs targeting various diseases.
• Ligand & Catalyst Development: The pyrazine nitrogen atoms can act as coordination sites, making it useful for developing new ligands and catalysts in organometallic chemistry.
• Functional Material Research: Employed as a monomer or building block in the development of advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses producing specialized compounds for client projects.

Basic Information

Product Name	tert-Butyl 2-Cyano-2-(Pyrazin-2-Yl)Acetate
CAS No.	930395-88-3
Molecular Formula	C11H13N3O2
Molecular Weight	219.24 g/mol
Synonyms	2-(Pyrazin-2-yl)-2-cyanoacetic acid tert-butyl ester; tert-Butyl (cyano)(pyrazin-2-yl)acetate; 2-Cyano-2-(2-pyrazinyl)acetic acid 1,1-dimethylethyl ester; Acetic acid, 2-cyano-2-(2-pyrazinyl)-, 1,1-dimethylethyl ester; t-Butyl 2-cyano-2-(pyrazin-2-yl)acetate; 2-Pyrazineacetic acid, α-cyano-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-cyano-2-(pyrazin-2-yl)acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each batch to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.