Description

2-Amino-4,5-Dimethyl-1-(2-Piperazin-1-Ylethyl)-1H-Pyrrole-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrole-piperazine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile pyrrole-piperazine scaffold.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Biochemical Probe Development: Serves as a precursor for creating specialized probes to study biological pathways and receptor interactions.
• Fine Chemical Synthesis: Used in multi-step organic syntheses requiring a functionalized, nitrogen-rich heterocyclic component.

Basic Information

Product Name	2-Amino-4,5-Dimethyl-1-(2-Piperazin-1-Ylethyl)-1H-Pyrrole-3-Carbonitrile
CAS No.	929974-71-0
Molecular Formula	C13H21N5
Molecular Weight	247.34 g/mol
Synonyms	1H-Pyrrole-3-carbonitrile, 2-amino-4,5-dimethyl-1-[2-(1-piperazinyl)ethyl]-; 2-Amino-4,5-dimethyl-1-[2-(piperazin-1-yl)ethyl]-1H-pyrrole-3-carbonitrile; 1-(2-Piperazin-1-ylethyl)-2-amino-4,5-dimethyl-1H-pyrrole-3-carbonitrile; 929974-71-0; Pyrrole-3-carbonitrile derivative; Arylpiperazine pyrrole nitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4,5-Dimethyl-1-(2-Piperazin-1-Ylethyl)-1H-Pyrrole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.