Description

(R)-Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One CAS NO 929047-07-4 is a high-purity, chiral heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel, biologically active molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers engaged in the synthesis of complex APIs and fine chemicals requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and other therapeutic agents.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce the (R)-configured pyrrolopyrazinone scaffold into target molecules.
• Medicinal Chemistry Research: Employed in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space for drug discovery.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects requiring this specific chiral template.

Basic Information

Product Name	(R)-Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One
CAS No.	929047-07-4
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(R)-Octahydropyrrolo[1,2-a]pyrazin-4-one; (R)-1,2,3,3a,4,5,6,7-Octahydropyrrolo[1,2-a]pyrazin-4-one; (R)-Hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one; (R)-Pyrrolo[1,2-a]pyrazin-4(1H)-one, hexahydro-; (R)-HPO; (R)-enantiomer of Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One
EINECS	Contact for details

Quality Control

Our (R)-Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.