Description

tert-Butyl 6-Chloropyrazin-2-Yl(Methyl)Carbamate is a high-purity chemical intermediate of significant importance in modern pharmaceutical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily needed by research institutions, custom synthesis providers, and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those containing functionalized pyrazine rings.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the chloropyrazine moiety is a core structural feature.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Protecting Group Chemistry: The tert-butyl carbamate (Boc) group is utilized for the temporary protection of amine functionalities during multi-step synthetic sequences.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this specialized intermediate.
• Academic & Industrial R&D: Fundamental research in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	tert-Butyl 6-Chloropyrazin-2-Yl(Methyl)Carbamate
CAS No.	928825-98-3
Molecular Formula	C10H14ClN3O2
Molecular Weight	243.69 g/mol
Synonyms	tert-Butyl N-(6-chloropyrazin-2-yl)-N-methylcarbamate; Carbamic acid, N-(6-chloro-2-pyrazinyl)-N-methyl-, 1,1-dimethylethyl ester; 6-Chloro-N-methyl-N-(pyrazin-2-yl)carbamic acid tert-butyl ester; 2-((tert-Butoxycarbonyl)(methyl)amino)-6-chloropyrazine; Boc-6-chloro-2-(N-methylamino)pyrazine; tert-Butyl (6-chloro-2-pyrazinyl)(methyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Chloropyrazin-2-Yl(Methyl)Carbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.