Description

3-Boc-3,8-Diazabicyclo[4.2.0]Octane is a high-value, protected bicyclic diamine building block used in advanced organic synthesis and pharmaceutical research. This compound is critical for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical R&D, agrochemical research, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing constrained, nitrogen-rich bicyclic scaffolds.
• Medicinal Chemistry: Serves as a versatile building block for constructing libraries of novel compounds in hit-to-lead and lead optimization programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require sophisticated heterocyclic cores.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics: The protected diamine structure is valuable for creating conformationally restricted peptide analogs.
• Chemical Biology Probes: Useful for synthesizing tool compounds and probes to study biological pathways and enzyme function.

Basic Information

Product Name	3-Boc-3,8-Diazabicyclo[4.2.0]Octane
CAS No.	928754-14-7
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl 3,8-diazabicyclo[4.2.0]octane-3-carboxylate; 3-(tert-Butoxycarbonyl)-3,8-diazabicyclo[4.2.0]octane; 3-Boc-3,8-diazabicyclo[4.2.0]octane; 3,8-Diazabicyclo[4.2.0]octane-3-carboxylic acid, 1,1-dimethylethyl ester; Bicyclo[4.2.0]octane-3,8-diamine, N3-Boc-protected; 3-N-Boc-3,8-diazabicyclo[4.2.0]octane
EINECS	Contact for details

Quality Control

Our 3-Boc-3,8-Diazabicyclo[4.2.0]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.