Description

Peg22 CAS NO 928211-42-1 is a high-purity polyethylene glycol (PEG) derivative, specifically a 22-unit PEG chain, valued for its excellent solubility, low toxicity, and versatile chemical functionality. This compound is essential for modifying the physicochemical properties of molecules, enhancing their solubility, stability, and biocompatibility for advanced applications. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality PEGylation reagents.

Application

• Pharmaceutical PEGylation: Conjugation to therapeutic proteins, peptides, and oligonucleotides to improve pharmacokinetics, reduce immunogenicity, and enhance circulatory half-life.
• Bioconjugation & Linker Chemistry: Serves as a hydrophilic spacer or linker in the synthesis of antibody-drug conjugates (ADCs), diagnostic probes, and targeted drug delivery systems.
• Polymer & Material Science: A key monomer or modifier for creating biocompatible hydrogels, surface coatings, and functionalized nanoparticles for biomedical and sensor applications.
• Cosmetic & Personal Care Formulations: Used as a humectant, solvent, or viscosity modifier in high-performance skincare and haircare products.
• Chemical Synthesis Intermediate: Provides a reactive handle for further functionalization in organic synthesis and the production of specialty surfactants and lubricants.

Basic Information

Item	Detail
Product Name	Peg22
CAS No.	928211-42-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polyethylene Glycol 22; PEG-22; 22-Mer Polyethylene Glycol; α-Hydro-ω-hydroxy-poly(oxy-1,2-ethanediyl); Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy- (22 mol EO average molar ratio); PEG 1000 (approximate MW); Macrogol 1000; Polyoxyethylene (22)
EINECS	Contact for details

Quality Control

Our Peg22 is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and functionality, suitable for research and cGMP manufacturing. Certificates of Analysis (COA) documenting purity (by HPLC/NMR), molecular weight distribution, and residual solvent levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Average Molecular Weight	As per customer grade requirement
Polydispersity Index (PDI)	≤ 1.05
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.