Description

(R)-1-n-Boc-3-Isopropylpiperazine is a high-purity, chiral piperazine derivative that serves as a critical building block in modern organic synthesis. This compound is essential for the development of enantiomerically pure pharmaceuticals and advanced materials, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of enantioselective pesticides and herbicides.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Peptidomimetics & Molecular Scaffolds: Integral for constructing constrained peptide analogs and privileged structures in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	(R)-1-n-Boc-3-Isopropylpiperazine
CAS No.	928025-63-2
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(R)-1-(tert-Butoxycarbonyl)-3-(propan-2-yl)piperazine; (R)-3-Isopropyl-1-Boc-piperazine; (R)-1-Boc-3-isopropylpiperazine; tert-Butyl (R)-3-isopropylpiperazine-1-carboxylate; (R)-1-N-Boc-3-isopropylpiperazine; (R)-N-Boc-3-isopropylpiperazine; (R)-3-(1-Methylethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (R)-1-n-Boc-3-Isopropylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.