Description

(S)-1-Boc-3-Isobutylpiperazine is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceutical agents, particularly in the creation of active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of peptidomimetics, enzyme inhibitors, and other specialized therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Synthesis: Used to introduce the (S)-3-isobutylpiperazine moiety into peptide backbones to modulate biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and protein interactions.
• Custom Synthesis Building Block: Provides a versatile, Boc-protected amine handle for multi-step synthetic routes in medicinal chemistry.

Basic Information

Product Name	(S)-1-Boc-3-Isobutylpiperazine
CAS No.	928025-62-1
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	(S)-tert-Butyl 3-isobutylpiperazine-1-carboxylate; (S)-1-(tert-Butoxycarbonyl)-3-isobutylpiperazine; (S)-N-Boc-3-isobutylpiperazine; (S)-3-Isobutyl-1-Boc-piperazine; (S)-1-Boc-3-(2-methylpropyl)piperazine; (S)-Piperazine-1-carboxylic acid, 3-(2-methylpropyl)-, 1,1-dimethylethyl ester; (S)-Boc-3-isobutylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-3-Isobutylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.