Description

(S)-1-Boc-3-Butylpiperazine is a high-purity chiral piperazine derivative, a crucial building block in modern organic synthesis. Its value lies in providing a stereochemically defined, protected amine framework essential for constructing complex molecules with high biological relevance. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral therapies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors for antiviral applications.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Chemistry: Integral for constructing peptidomimetic scaffolds that mimic peptide structure and function for drug discovery.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	(S)-1-Boc-3-Butylpiperazine
CAS No.	928025-60-9
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-3-butylpiperazine; (S)-3-Butyl-1-Boc-piperazine; tert-Butyl (S)-3-butylpiperazine-1-carboxylate; (S)-1-Boc-3-n-butylpiperazine; (S)-N-Boc-3-butylpiperazine; (3S)-1-(tert-Butoxycarbonyl)-3-butylpiperazine; (S)-1-Boc-3-butyl-piperazine; (S)-1-N-Boc-3-butylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-3-Butylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee reproducible quality and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.