Description

(S)-1-Boc-3-Propylpiperazine is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Ligand and Catalyst Development: Used to create novel chiral ligands for asymmetric catalysis and organometallic complexes.
• Peptidomimetics Research: Serves as a constrained scaffold in the design and synthesis of peptide analogs and mimetics.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and receptor interactions.
• Agrochemical Synthesis: An intermediate in the development of advanced, chiral agrochemicals.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	(S)-1-Boc-3-Propylpiperazine
CAS No.	928025-58-5
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-3-propylpiperazine; (S)-3-Propyl-1-Boc-piperazine; tert-Butyl (S)-3-propylpiperazine-1-carboxylate; (S)-1-Boc-3-propylpiperazine; (S)-N-Boc-3-propylpiperazine; (S)-1-(tert-Butyloxycarbonyl)-3-propylpiperazine; (S)-3-n-Propyl-1-Boc-piperazine; (S)-1-Boc-3-n-propylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-3-Propylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.