Description

(R)-1-Boc-3-Propylpiperazine is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a specific stereochemical configuration into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	(R)-1-Boc-3-Propylpiperazine
CAS No.	928025-57-4
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-3-propyl-(R)-piperazine; tert-Butyl (R)-3-propylpiperazine-1-carboxylate; (R)-1-(tert-Butoxycarbonyl)-3-propylpiperazine; (R)-3-Propyl-1-Boc-piperazine; (R)-N-Boc-3-propylpiperazine; (R)-1-N-Boc-3-propylpiperazine; (3R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-3-propylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Boc-3-Propylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.