Description

(S)-1-n-Boc-3-Ethylpiperazine is a high-purity, chiral piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly for chiral drugs targeting the central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this Boc-protected intermediate for constructing complex molecular architectures with precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) requiring a specific (S)-configured piperazine scaffold.
• Asymmetric Synthesis: Employed as a building block in asymmetric catalysis and synthesis to introduce chirality into target molecules.
• Ligand and Catalyst Preparation: Useful for the preparation of chiral ligands and organocatalysts used in enantioselective transformations.
• Peptidomimetic Research: Serves as a constrained diamine analogue in the design and synthesis of peptidomimetics and bioactive peptides.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological systems and enzyme interactions.

Basic Information

Product Name	(S)-1-n-Boc-3-Ethylpiperazine
CAS No.	928025-56-3
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-3-ethylpiperazine; (S)-3-Ethyl-1-Boc-piperazine; (S)-1-Boc-3-ethylpiperazine; tert-Butyl (S)-3-ethylpiperazine-1-carboxylate; (S)-1-N-Boc-3-ethylpiperazine; (S)-3-Ethylpiperazine-1-carboxylic acid tert-butyl ester; (S)-N-Boc-3-ethylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-n-Boc-3-Ethylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.