Description

(R)-1-Benzyl-3-Isobutylpiperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial building block for the development of novel pharmaceutical intermediates and active ingredients. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Asymmetric Synthesis: Used as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Precursor for Fine Chemicals: Acts as a starting material for the synthesis of more complex, value-added specialty chemicals.

Basic Information

Product Name	(R)-1-Benzyl-3-Isobutylpiperazine
CAS No.	928025-44-9
Molecular Formula	C15H24N2
Molecular Weight	232.37 g/mol
Synonyms	(R)-1-Benzyl-3-(2-methylpropyl)piperazine; (R)-3-Isobutyl-1-benzylpiperazine; (R)-1-Benzyl-3-isobutyl-piperazine; (R)-1-Benzyl-3-(isobutyl)piperazine; (R)-N-Benzyl-3-isobutylpiperazine; (3R)-1-Benzyl-3-(2-methylpropyl)piperazine; (R)-1-Bzl-3-iBu-piperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-3-Isobutylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.