Description

1-(3-Nitro-4-Piperazin-1-Ylphenyl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct nitro and piperazine-substituted aromatic ketone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is an essential building block for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent drug candidates, especially in neurological and oncology research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex molecular architectures via its reactive ketone and aromatic nitro groups.
• Research & Development (R&D): Serves as a standard or starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of specific APIs under controlled Good Manufacturing Practice (GMP) environments.
• Biochemical Research: Utilized in the development of enzyme inhibitors or receptor ligands due to its piperazine moiety.

Basic Information

Product Name	1-(3-Nitro-4-Piperazin-1-Ylphenyl)Ethanone
CAS No.	926257-88-7
Molecular Formula	C12H15N3O3
Molecular Weight	249.27 g/mol
Synonyms	1-(3-Nitro-4-(piperazin-1-yl)phenyl)ethan-1-one; 1-[3-Nitro-4-(1-piperazinyl)phenyl]ethanone; Ethanone, 1-[3-nitro-4-(1-piperazinyl)phenyl]-; 3-Nitro-4-piperazin-1-ylacetophenone; 4-Acetyl-2-nitro-1-piperazinobenzene; 1-(4-Piperazin-1-yl-3-nitrophenyl)ethanone; 926257-88-7
EINECS	Contact for details

Quality Control

Our 1-(3-Nitro-4-Piperazin-1-Ylphenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.