Description

1-[(3-Fluorophenyl)Acetyl]Piperazine Hydrochloride is a high-purity, fluorinated piperazine derivative offered as a hydrochloride salt, providing enhanced stability and handling properties. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its specific fluorinated aromatic and piperazine pharmacophore into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides, leveraging the fluorine atom for improved bioactivity and metabolic stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-[(3-Fluorophenyl)Acetyl]Piperazine Hydrochloride
CAS No.	926226-12-2
Molecular Formula	C12H15FClN2O
Molecular Weight	254.71 g/mol
Synonyms	1-(3-Fluorophenacyl)piperazine hydrochloride; 1-[2-(3-Fluorophenyl)-2-oxoethyl]piperazine hydrochloride; 3-Fluorophenacyl piperazine hydrochloride; N-(3-Fluorophenacyl)piperazine hydrochloride; 926226-12-2; 1-[(3-Fluorophenyl)-2-oxoethyl]piperazine HCl
EINECS	Contact for details

Quality Control

Our 1-[(3-Fluorophenyl)Acetyl]Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and results. Our quality commitment ensures material suitable for GMP and ICH Q7 compliant synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.