Description

4-(4-Aminobenzoyl)Piperazin-2-One is a high-purity, specialized organic building block featuring both an aromatic amine and a piperazinone moiety. This compound matters as a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in novel drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs.
• Protease Inhibitor Synthesis: Used in constructing molecular scaffolds for potential protease inhibitors due to its piperazinone core.
• Kinase Inhibitor Development: Serves as a building block in the creation of novel kinase inhibitor candidates for oncology research.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.
• Academic & Industrial R&D: Fundamental material for methodological studies in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	4-(4-Aminobenzoyl)Piperazin-2-One
CAS No.	926221-91-2
Molecular Formula	C11H13N3O2
Molecular Weight	219.24 g/mol
Synonyms	4-(4-Aminobenzoyl)-2-piperazinone; 1-(4-Aminobenzoyl)piperazin-2-one; 4-Aminophenyl(2-oxopiperazin-1-yl)methanone; 2-Piperazinone, 4-(4-aminobenzoyl)-; 926221-91-2; 4-(4-Aminobenzoyl)-2-piperazinone; 4-(4-Aminobenzoyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Aminobenzoyl)Piperazin-2-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.