Description

1-(2,4-Difluorobenzoyl)Piperazine is a high-purity, fluorinated piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antimicrobial agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluorobenzoyl moiety can enhance biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Utilized in the development of specialized ligands for catalysis or as a component in metal-organic frameworks (MOFs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and custom synthesis manufacturers producing tailored compounds for client projects.

Basic Information

Product Name	1-(2,4-Difluorobenzoyl)Piperazine
CAS No.	926209-09-8
Molecular Formula	C11H12F2N2O
Molecular Weight	226.22 g/mol
Synonyms	1-(2,4-Difluorobenzoyl)piperazine; 2,4-Difluoro-N-(piperazin-1-yl)benzamide; Piperazine, 1-(2,4-difluorobenzoyl)-; N-(2,4-Difluorobenzoyl)piperazine; 926209-09-8
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorobenzoyl)Piperazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and agrochemical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.