Description

Ethyl 4-(2-[4-(Methylsulfonyl)Phenyl]-2-Oxoethyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions, including alkylations, condensations, and cyclizations, to construct complex nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies in drug discovery programs, enabling the exploration of new pharmacophores.
• Process Development & Scale-Up: Employed in the optimization and kilogram-scale production of target molecules for pre-clinical and clinical trial material supply.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 4-(2-[4-(Methylsulfonyl)Phenyl]-2-Oxoethyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	924869-22-7
Molecular Formula	C₁₆H₂₂N₂O₅S
Molecular Weight	354.42 g/mol
Synonyms	Ethyl 1,2,3,6-tetrahydro-4-[2-oxo-2-[4-(methylsulfonyl)phenyl]ethyl]-2-pyrazinecarboxylate; 4-[2-Oxo-2-(4-methylsulfonylphenyl)ethyl]tetrahydropyrazine-1(2H)-carboxylic acid ethyl ester; 924869-22-7; UNII-9Q3J2F7F2I; 9Q3J2F7F2I; AKOS040757585; SCHEMBL21816727; DTXSID60636670
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2-[4-(Methylsulfonyl)Phenyl]-2-Oxoethyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.