Description

(4-Bromo-2-Fluorophenyl)(4-Methylpiperazin-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated aromatic ketone structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo-fluoro and piperazine motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research programs.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its halogen and piperazine functional groups.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new pesticides and herbicides.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Academic Research: Used in university and institutional labs for novel heterocyclic and fluorine chemistry research.

Basic Information

Product Name	(4-Bromo-2-Fluorophenyl)(4-Methylpiperazin-1-Yl)Methanone
CAS No.	924642-60-4
Molecular Formula	C12H14BrFN2O
Molecular Weight	301.16 g/mol
Synonyms	1-(4-Bromo-2-fluorobenzoyl)-4-methylpiperazine; 4-Methyl-1-(4-bromo-2-fluorobenzoyl)piperazine; (4-Bromo-2-fluorophenyl)-(4-methylpiperazin-1-yl)methanone; 4-Bromo-2-fluoro-N-(4-methylpiperazin-1-yl)benzamide; 924642-60-4; Methanone, (4-bromo-2-fluorophenyl)(4-methyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our (4-Bromo-2-Fluorophenyl)(4-Methylpiperazin-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.