Description

1,3-Dihydro-1-[1-[(5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thien-2-Yl)Carbonyl]-4-Piperidinyl]-2H-Benzimidazol-2-One is a high-purity, complex heterocyclic compound serving as a critical advanced intermediate in pharmaceutical research and development. This compound matters because it provides a structurally defined building block essential for synthesizing novel active pharmaceutical ingredients (APIs), enabling medicinal chemistry programs to explore new therapeutic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the discovery and optimization of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic building block for the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop novel therapeutic agents.
• Process Chemistry Development: Serves as a defined intermediate for scaling up synthetic routes and optimizing manufacturing processes for potential drug substances.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global pharmaceutical companies.

Basic Information

Product Name	1,3-Dihydro-1-[1-[(5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thien-2-Yl)Carbonyl]-4-Piperidinyl]-2H-Benzimidazol-2-One
CAS No.	924377-85-5
Molecular Formula	C22H23N3O2S
Molecular Weight	393.50 g/mol
Synonyms	1-(1-((5,6,7,8-Tetrahydro-4H-cyclohepta[b]thiophen-2-yl)carbonyl)piperidin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one; 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one; 924377-85-5; UNII-9F4F8S8A4R; 9F4F8S8A4R; CHEMBL3183453; BDBM50157873; AKOS025147212.
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-1-[1-[(5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thien-2-Yl)Carbonyl]-4-Piperidinyl]-2H-Benzimidazol-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.