Description

2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]-5-Nitrobenzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and optimization of new therapeutic agents, particularly within central nervous system (CNS) and other targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• CNS Drug Development: Serves as a core scaffold for research into potential treatments for neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological studies.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and drug discovery projects.

Basic Information

Product Name	2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]-5-Nitrobenzonitrile
CAS No.	924072-98-0
Molecular Formula	C20H20N4O4
Molecular Weight	380.40 g/mol
Synonyms	5-Nitro-2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]benzonitrile; 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-5-nitrobenzonitrile; 924072-98-0; 2-[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]-5-nitrobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.